Not in the way you might think, when you hear the word "detox". Let me take an excerpt from one of my 2017 posts on cleansing:

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There are indeed gentle ways of helping the liver using select foods, juices and herbal supplements to support the liver to do what it's already more than capable of doing. The alternative (rapid methods of cleansing, or fasting while not under medical supervision or receiving approval or support from your doctor) may end you up in the hospital in life-threatening conditions. The fact of the matter is, our bodies can't detoxify themselves completely. For example, even when we are demanded to release fat-stored toxins by actually burning through our fat stores, the effects of the freely circulating toxins may wreak havoc on the body, and some molecules cannot be eliminated as quickly as they are released. That is why it's important to eat lots of vegetables, fruits, and fiber-rich compounds, choose antioxidant-rich foods to quench inflammation, and drink lots of fluids to help your intestines, kidneys, skin and liver to do their job to their fullest potential!

I think of juicing as a way to rapidly infuse your body with nutrients that enable it to do what it's already supposed to do, which is to provide nutrients and hydration allow the kidneys, liver, and sweat to process the blood and urine as they normally should. Juice cleansing or fasting itself is not something you should consider without the supervision of a doctor and/or dietitian if you want to do it for longer than a day or so, or if you have pre-existing medical conditions of the kidneys, liver, heart, or diabetes.

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In my personal experience, drinking only fresh squeezed vegetable and fruit juice (primarily vegetables) is a kind and non-drastic way to "reset your tastebuds" and increase cravings for fresher foods.